I didn't realise that in drupal 6, with a little bit of trickery you can add a template region to a node template and not just the page template - it makes sense really and means that you can easily place blocks into nodes once you have added a region or 2. In some cases this might help you build a more block centric version of your target web design in drupal. Here's an article that shows how it's done:

http://www.kirkdesigns.co.uk/drupal-6-how-embed-region-node

Block on!